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Page 1
BET bromodomain inhibitors synergize with ATR inhibitors in melanoma.
Cell Death Dis. 2017 Aug 10;8(8):e2982. doi: 10.1038/cddis.2017.383.
Cell Death Dis. 2017.
PMID: 28796244
Free PMC article.
Subcellular Distribution of p53 by the p53-Responsive lncRNA NBAT1 Determines Chemotherapeutic Response in Neuroblastoma.
Mitra S, Muralidharan SV, Di Marco M, Juvvuna PK, Kosalai ST, Reischl S, Jachimowicz D, Subhash S, Raimondi I, Kurian L, Huarte M, Kogner P, Fischer M, Johnsen JI, Mondal T, Kanduri C.
Mitra S, et al.
Cancer Res. 2021 Mar 15;81(6):1457-1471. doi: 10.1158/0008-5472.CAN-19-3499. Epub 2020 Dec 28.
Cancer Res. 2021.
PMID: 33372039
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Cancer Differentiating Agent Hexamethylene Bisacetamide Inhibits BET Bromodomain Proteins.
Nilsson LM, Green LC, Muralidharan SV, Demir D, Welin M, Bhadury J, Logan DT, Walse B, Nilsson JA.
Nilsson LM, et al.
Cancer Res. 2016 Apr 15;76(8):2376-83. doi: 10.1158/0008-5472.CAN-15-2721. Epub 2016 Mar 3.
Cancer Res. 2016.
PMID: 26941288
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Small molecule inhibitors and a kinase-dead expressing mouse model demonstrate that the kinase activity of Chk1 is essential for mouse embryos and cancer cells.
Muralidharan SV, Nilsson LM, Lindberg MF, Nilsson JA.
Muralidharan SV, et al.
Life Sci Alliance. 2020 Jun 22;3(8):e202000671. doi: 10.26508/lsa.202000671. Print 2020 Aug.
Life Sci Alliance. 2020.
PMID: 32571801
Free PMC article.
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Therapeutic implications for the induced levels of Chk1 in Myc-expressing cancer cells.
Höglund A, Nilsson LM, Muralidharan SV, Hasvold LA, Merta P, Rudelius M, Nikolova V, Keller U, Nilsson JA.
Höglund A, et al.
Clin Cancer Res. 2011 Nov 15;17(22):7067-79. doi: 10.1158/1078-0432.CCR-11-1198. Epub 2011 Sep 20.
Clin Cancer Res. 2011.
PMID: 21933891
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Aberrant fat metabolism in Caenorhabditis elegans mutants with defects in the defecation motor program.
Sheng M, Hosseinzadeh A, Muralidharan SV, Gaur R, Selstam E, Tuck S.
Sheng M, et al.
PLoS One. 2015 Apr 7;10(4):e0124515. doi: 10.1371/journal.pone.0124515. eCollection 2015.
PLoS One. 2015.
PMID: 25849533
Free PMC article.
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BET and HDAC inhibitors induce similar genes and biological effects and synergize to kill in Myc-induced murine lymphoma.
Bhadury J, Nilsson LM, Muralidharan SV, Green LC, Li Z, Gesner EM, Hansen HC, Keller UB, McLure KG, Nilsson JA.
Bhadury J, et al.
Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):E2721-30. doi: 10.1073/pnas.1406722111. Epub 2014 Jun 16.
Proc Natl Acad Sci U S A. 2014.
PMID: 24979794
Free PMC article.
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